Brainier than Thou

26th July 2010

A little while ago, we learned that extra body fat was correlated with smaller brain volume and possibly linked to increased rates of Alzheimer’s disease.  Across the city, ice cream spoons were sadly set aside.  Not that anyone wanted to be overweight, but being overweight and hopelessly confused was just more than we could bear.

Now in the latest, “Health Findings You Can’t Do Anything About” News, comes evidence that those with large heads are less likely to suffer the ravages of Alzheimer’s disease, ostensibly because they possess a vast storehouse of spare brain cells.

This is great news if you have a freakishly large head.  Sure, it makes makes wearing a stylish hat all but an impossibility, but now you can rest assured that your brain has potentially been stockpiling cells for later in life when you need a few extras.  Lucky you!

However, for those of you with normally proportioned heads, this news is of little value as there is essentially nothing you can do to change the size of your brain or the number of cells piled up in there.  No brain-building exercise machine that will be offered on late night television.  No neuron multiplication diet that will bulk up your cerebellum.

Most brain growth occurs before the age of 6.  Any differential in growing that storeroom of spare cells would need to be accomplished in the pre-school years.  Factors leading to optimal brain growth would include genetics, nutrition, general good health, and avoiding injury.

The average head circumference is 56 centimeters (and the weight of the average human head is 8 pounds – thank you, “Jerry MacGuire”).  A head bigger than the average could be less impacted by brain atrophy, while smaller brains with less grey matter to spare might be more susceptible to damage.

Excuse me while I go find my tape measure, I want to see how big my extra stash of memory is!  How do you measure up?

806,000 hip and knee implants were performed in the US in 2007 – that’s double the amount done a decade earlier. However, a 2007 study demonstrates that 7% of Medicare patients who underwent a hip replacement required another replacement hip within seven and a half years.  That number, small as it sounds, translates into thousands of patients who eventually need a “do over”. A joint surgery involves risk, pain, convalescence, rehab and medical expenses; no one wants to go through that more than once if necessary.

A National Joint Replacement Registry helps reduce the rate of failed procedures by keeping a database of information that keys in surgeons to problematic implants, and provides insight as to how to avoid mess ups. According to Dr. Daniel Berry, chief of orthopedic surgery at the Mayo Clinic in Rochester, Minn,  “Every country that has developed a registry has been able to reduce failure rates significantly.”  Sweden is one case in point.

The newly formed American Joint Replacement Registry is still in its nascent stage and has started collecting data. Its goal is to improve the quality, outcomes, and cost-effectiveness of total joint replacement (TJR) surgeries through the achievement of four objectives:

1. Establish an infrastructure and a uniform system for the collecting device information and monitoring outcomes of TJR throughout the U.S.;

2. Identify patients who may need follow-up evaluation thereby increasing patient safety;

3. Create real-time survivorship curve in order to detect poorly performing implants;

4. Establish a uniform system that can be used to define the epidemiology of TJR for outcomes research to improve the quality and outcomes of patient care.

Until we have access to solid facts from the U.S. Registry, there are some proactive steps you can take if you are in the market for a new joint.

– Go with a highly experienced surgeon in a busy hospital; don’t look for the best deal. Ask for recommendations. A 2004 study published in The Journal of Bone and Joint Surgery found that patients receiving knee replacements from doctors who performed more than 50 of the procedures a year had fewer complications than patients whose surgeons did 12 procedures or fewer a year.

A similar trend was documented with hospital volume. Patients at hospitals that performed more than 200 knee replacements a year fared better than patients at hospitals that performed 25 or fewer.

– A joint replacement is not for everyone. Some arthritic problems are better served with medication, and surgery may be too risky for those who have uncontrolled high blood pressure or another serious chronic condition.

– Research the joint implant that your surgeon recommends. Find out how well it has performed in others and if there are known complications. Some implants are somewhat controversial and may cause tissue and bone damage; newer doesn’t necessarily mean better. If the hospital has its own registry, ask to review the data.

– Educate yourself as to what the surgery entails. The American Academy of Orthopaedic Surgeon’s patient information Web site, orthoinfo.org is very helpful.

– Prepare your recovery in advance. Arrange for the necessary support upon your return home, and make sure you have all the help you need. It is crucial not to overexert yourself during your initial healing period.